Visible-light-promoted direct C3-trifluoromethylation and perfluoroalkylation of imidazopyridines-Reference-Cited by-同舟云学术

Visible-light-promoted direct C3-trifluoromethylation and perfluoroalkylation of imidazopyridines

Published:2021 Issue:38 Volume:19 Page:8301-8306
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Li Meichen¹,Li Gaolin¹,Dai Chenxun¹,Zhou Wenjun¹,Zhan Wenqiang¹,Gao Muyang¹^ORCID,Rong Yuan¹,Tan Ze¹^ORCID,Deng Wei¹

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China

Abstract

Highly mono-selective trifluoromethylation and perfluoroalkylation at C3 of imidazo[1,2-a]pyridines were achieved via visible-light-promoted C–H bond functionalization of imidazo[1,2-a]pyridines without using any photoredox catalyst.

Funder

Natural Science Foundation of Hunan Province

Hunan University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01417J

Reference64 articles.

1. Copper catalyzed tandem oxidative C–H amination/cyclizations: Direct access to imidazo[1,2-a]pyridines

2. Imidazo[1,2-a]pyridines Susceptible to Excited State Intramolecular Proton Transfer: One-Pot Synthesis via an Ortoleva–King Reaction