Diruthenium(ii,iii) metallodrugs of ibuprofen and naproxen encapsulated in intravenously injectable polymer–lipid nanoparticles exhibit enhanced activity against breast and prostate cancer cells-Reference-Cited by-同舟云学术

Diruthenium(ii,iii) metallodrugs of ibuprofen and naproxen encapsulated in intravenously injectable polymer–lipid nanoparticles exhibit enhanced activity against breast and prostate cancer cells

Published:2017 Issue:30 Volume:9 Page:10701-10714
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Alves Rico Samara R.¹²³⁴⁵^ORCID,Abbasi Azhar Z.⁶⁷⁸⁹¹⁰^ORCID,Ribeiro Geise¹²³⁴⁵,Ahmed Taksim⁶⁷⁸⁹¹⁰^ORCID,Wu Xiao Yu⁶⁷⁸⁹¹⁰^ORCID,de Oliveira Silva Denise¹²³⁴⁵^ORCID

Affiliation:

1. Laboratory for Synthetic and Structural Inorganic Chemistry - Bioinorganic and Metallodrugs

2. Department of Fundamental Chemistry

3. Institute of Chemistry

4. University of São Paulo

5. São Paulo

6. Advanced Pharmaceutics and Drug Delivery Laboratory

7. Leslie Dan Faculty of Pharmacy

8. University of Toronto

9. Toronto

10. Canada

Abstract

Stable nanoformulations of diruthenium(ii,iii)-NSAID metallodrugs encapsulated in intravenously injectable polymer-lipid NPs have been prepared and tested in cancer cells.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Natural Sciences and Engineering Research Council of Canada

São Paulo Research Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NR/C7NR01582H

Reference66 articles.

1. S. Dhar and S. J.Lippard, Current status and mechanism of action of platinum-based anticancer drugs, in Bioinorganic Medicinal Chemistry, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2011

2. Targeting and delivery of platinum-based anticancer drugs

3. Nanocarriers for delivery of platinum anticancer drugs

4. Perspectives for Novel Mixed Diruthenium-Organic Drugs as Metallopharmaceuticals in Cancer Therapy

5. D. de Oliveira Silva , Ruthenium Compounds Targeting Cancer Therapy, in Frontiers in Anti-cancer Drug Discovery, ed. Atta-ur-Rahman and M. I. Choudhary, Bentham Science Publishers, Sharjah, U.A.E., 2014, vol. 4

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