Acrylic-based culture plate format perfusion device to establish liver endothelial–epithelial interface-Reference-Cited by-同舟云学术

Acrylic-based culture plate format perfusion device to establish liver endothelial–epithelial interface

Published:2023 Issue:13 Volume:23 Page:3106-3119
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

McDuffie Dennis¹,Alver Charles G.¹,Suthar Bhumi¹,Helm Madeline¹,Oliver David¹,Burgess R. Alan²,Barr David²,Thomas Emmanuel²³,Agarwal Ashutosh¹³⁴^ORCID

Affiliation:

1. Department of Biomedical Engineering, University of Miami, Coral Gables, FL, USA

2. Department of Pathology & Laboratory Medicine, Schiff Center for Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA

3. Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, USA

4. Desai Sethi Urology Institute, University of Miami Miller School of Medicine, USA

Abstract

Mimicking hepatic acinus architecture and physiological function within a modular Liver on a Chip has a profound effect on hepatocyte function, and motivates future study of multi-organ interactions.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of General Medical Sciences

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00382E

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