Natural products targeting the elongation phase of eukaryotic protein biosynthesis
Author:
Affiliation:
1. Department of Chemical Biology
2. Helmholtz Centre for Infection Research
3. 38124 Braunschweig
4. Germany
5. Center of Biomolecular Drug Research (BMWZ)
Abstract
This review highlights different mechanisms how natural products interfere with the elongation phase of eukaryotic protein biosynthesis, and it discusses therapeutic applications thereof.
Funder
Helmholtz Association
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/NP/D0NP00011F
Reference80 articles.
1. Eukaryotic Protein Synthesis: Still a Mystery
2. A mechanistic overview of translation initiation in eukaryotes
3. Toward a Kinetic Understanding of Eukaryotic Translation
4. The Elongation, Termination, and Recycling Phases of Translation in Eukaryotes
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Analysis of Haemonchus embryos at single cell resolution identifies two eukaryotic elongation factors as intervention target candidates;Computational and Structural Biotechnology Journal;2024-12
2. The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma;Current Cancer Drug Targets;2024-07-05
3. Recombinant Protein Expression and Its Biotechnological Applications in Chlorella spp.;SynBio;2024-06-06
4. Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway;iScience;2024-06
5. Using nanotechnology to progress the utilization of marine natural products in combating multidrug resistance in cancer: A prospective strategy;Journal of Biochemical and Molecular Toxicology;2024-05-20
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3