Differential toxicity of gold-doxorubicin in cancer cells vs. cardiomyocytes as measured by real-time growth assays and fluorescence lifetime imaging microscopy (FLIM)-Reference-Cited by-同舟云学术

Differential toxicity of gold-doxorubicin in cancer cells vs. cardiomyocytes as measured by real-time growth assays and fluorescence lifetime imaging microscopy (FLIM)

Published:2015 Issue:16 Volume:140 Page:5732-5741
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Tawagi Eric¹²³⁴,Massmann Charlotte¹²³⁴⁵,Chibli Hicham¹²³⁴,Nadeau Jay L.¹²³⁴

Affiliation:

1. Department of Biomedical Engineering

2. McGill University

3. Montreal

4. Canada

5. Biomedical Technologies

Abstract

The kinetics of toxicity of doxorubicin (Dox) and gold nanoparticle-conjugated doxorubicin (Au-Dox) were investigated in cultured B16 melanoma cells and cardiomyocytes using real-time cell-growth imaging.

Funder

Natural Sciences and Engineering Research Council of Canada

Canadian Institutes of Health Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AN/C5AN00446B

Reference42 articles.

1. Prevention of Anthracycline-Induced Cardiotoxicity

2. An update on the risk prediction and prevention of anticancer therapy-induced cardiotoxicity