Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents-Reference-Cited by-同舟云学术

Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents

Published:2018 Issue:10 Volume:9 Page:1649-1662
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Maguire Casey J.¹²³⁴,Chen Zhi¹²³⁴,Mocharla Vani P.¹²³⁴,Sriram Madhavi¹²³⁴,Strecker Tracy E.¹²³⁴,Hamel Ernest⁵⁶⁷⁸⁹,Zhou Heling¹⁰¹¹¹²⁴,Lopez Ramona¹⁰¹¹¹²⁴,Wang Yifan¹²³⁴,Mason Ralph P.¹⁰¹¹¹²⁴^ORCID,Chaplin David J.¹²³⁴¹³,Trawick Mary Lynn¹²³⁴^ORCID,Pinney Kevin G.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry

2. Baylor University

3. Waco

4. USA

5. Screening Technologies Branch

6. Developmental Therapeutics Program

7. Division of Cancer Treatment and Diagnosis

8. National Cancer Institute

9. Frederick National Laboratory for Cancer Research

10. Department of Radiology

11. The University of Texas Southwestern Medical Center

12. Dallas

13. Mateon Therapeutics, Inc.

Abstract

Dihydronaphthalene analogues as potent inhibitors of tubulin polymerization, cytotoxic agents, and vascular disrupting agents (VDAs).

Funder

Cancer Prevention and Research Institute of Texas

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00322J

Reference68 articles.

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3. Antineoplastic Agents. 291. Isolation and Synthesis of Combretastatins A-4, A-5, and A-6

4. K. Pinney , G.Pettit , M.Trawick , C.Jelinek and D.Chaplin , in Anticancer Agents from Natural Products, Second Edition , CRC Press , 2011 , pp. 27–64

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