TEMPO promoted direct multi-functionalization of terminal alkynes with 2-oxindoles/benzofuran-2(3H)-one
Author:
Affiliation:
1. Beijing National Laboratory for Molecular Sciences (BNLMS)
2. CAS Key Laboratory of Molecular Recognition and Function
3. CAS Research/Education Center for Excellence in Molecular Sciences
4. Institute of Chemistry
5. Chinese Academy of Sciences
Abstract
Highly selective and catalyst-free tandem multi-functionalization of terminal alkynes was developed with 2-oxindoles and benzo-furan-2(3H)-one using TEMPO both as a radical promoter and a trapping reagent.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Beijing Municipality
China Association for Science and Technology
Chinese Academy of Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01380B
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4. Transition-Metal-Catalyzed Functionalization of Propargylic Alcohols and Their Derivatives
5. Transition metal-catalyzed addition of C-, N- and O-nucleophiles to unactivated C–C multiple bonds
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