The inhibitory role of intracellular free zinc in the regulation of Arg-1 expression in interleukin-4-induced activation of M2 microglia-Reference-Cited by-同舟云学术

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The inhibitory role of intracellular free zinc in the regulation of Arg-1 expression in interleukin-4-induced activation of M2 microglia

Published:2018 Issue:10 Volume:10 Page:1501-1509
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Aratake Takaaki¹²³⁴⁵^ORCID,Higashi Youichirou¹²³⁴⁵^ORCID,Ueba Yusuke⁶²³⁴⁵,Hamada Tomoya¹²³⁴⁵,Shimizu Takahiro¹²³⁴⁵,Shimizu Shogo¹²³⁴⁵^ORCID,Yawata Toshio⁶²³⁴⁵,Ueba Tetsuya⁶²³⁴⁵,Saito Motoaki¹²³⁴⁵

Affiliation:

1. Department of Pharmacology

2. Kochi Medical School

3. Kochi University

4. Nankoku 783-8505

5. Japan

6. Department of Neurosurgery

Abstract

Intracellular zinc plays an important role in neuroprotective M2-polarization of microglia.

Funder

Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care

Japan Society for the Promotion of Science

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MT/C8MT00248G

Reference40 articles.

1. Neurobiology of Zinc and Zinc-Containing Neurons

2. Hypoosmotic swelling affects zinc homeostasis in cultured rat astrocytes

3. Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation

4. Oxidative stress upregulates zinc uptake activity via Zrt/Irt-like protein 1 (ZIP1) in cultured mouse astrocytes

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