Engineering a highly selective probe for ratiometric imaging of H2Sn and revealing its signaling pathway in fatty liver disease-Reference-Cited by-同舟云学术

Engineering a highly selective probe for ratiometric imaging of H2Sn and revealing its signaling pathway in fatty liver disease

Published:2020 Issue:30 Volume:11 Page:7991-7999
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Li Wei¹²³⁴⁵,Wang Lu⁶⁷⁸⁹,Yin Shulu¹²³⁴⁵,Lai Huanhua¹²³⁴⁵,Yuan Lin¹²³⁴⁵^ORCID,Zhang Xiaobing¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics

2. College of Chemistry and Chemical Engineering

3. Hunan University

4. Changsha 410082

5. P. R. China

6. Department of Chemical Biology

7. Max Planck Institute for Medical Research

8. Heidelberg 69120

9. Germany

Abstract

A highly selective probe (PPG-Np-RhPhCO) used for revealing the intracellular H₂S_n signaling pathways in a nonalcoholic fatty liver disease (NAFLD) model.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC03336G

Reference64 articles.

1. Chemical Biology of H2S Signaling through Persulfidation

2. Small-molecule fluorescent probes for imaging gaseous signaling molecules: current progress and future implications

3. Hypothesis: the role of reactive sulfur species in oxidative stress

4. Rational Design and Bioimaging Applications of Highly Selective Fluorescence Probes for Hydrogen Polysulfides

5. Polysulfides Link H2S to Protein Thiol Oxidation

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