Spectro-electrochemical assessments of DNA/BSA interactions, cytotoxicity, radical scavenging and pharmacological implications of biosensitive and biologically active morpholine-based metal(ii) complexes: a combined experimental and computational investigation-Reference-Cited by-同舟云学术

Spectro-electrochemical assessments of DNA/BSA interactions, cytotoxicity, radical scavenging and pharmacological implications of biosensitive and biologically active morpholine-based metal(ii) complexes: a combined experimental and computational investigation

Published:2019 Issue:25 Volume:9 Page:14220-14241
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sakthikumar Karunganathan¹²³^ORCID,Solomon Rajadurai Vijay⁴⁵⁶³^ORCID,Raja Jeyaraj Dhaveethu⁴⁷⁸³^ORCID

Affiliation:

1. Chemistry Research Centre

2. Mohamed Sathak Engineering College

3. India

4. Department of Chemistry

5. Madras Christian College (Autonomous)

6. Chennai 600 059

7. The American College (Autonomous)

8. Madurai 625 002

Abstract

Morpholine-based metal(ii) complexes exhibited more significant biological activities than the free ligand. Among investigations towards DNA/BSA, the copper complex revealed excellent intercalating efficacy, which suggests it may have potential as a novel anticancer agent.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C8RA09218D

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