Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues-Reference-Cited by-同舟云学术

Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues

Published:2016 Issue:3 Volume:16 Page:599-610
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Marsano Anna¹²³⁴⁵,Conficconi Chiara¹²³⁴⁵,Lemme Marta¹²³⁴⁵,Occhetta Paola⁶⁷⁸⁹,Gaudiello Emanuele¹²³⁴⁵,Votta Emiliano⁶⁷⁸⁹^ORCID,Cerino Giulia¹²³⁴⁵,Redaelli Alberto⁶⁷⁸⁹,Rasponi Marco⁶⁷⁸⁹

Affiliation:

1. Departments of Surgery and Biomedicine

2. University Basel

3. University Hospital Basel

4. 4031 Basel

5. Switzerland

6. Department of Electronics, Information and Bioengineering

7. Politecnico di Milano

8. 20133 Milano

9. Italy

Abstract

The beating heart-on-a-chip (i) generates 3D cardiac constructs with well-defined geometries from cell-laden hydrogel prepolymers, (ii) provides uniaxial cyclic mechanical stimulation, (iii) allows efficient delivery of drugs and chemicals.

Funder

Fondazione Cariplo

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/LC/C5LC01356A

Reference38 articles.

1. Microfluidic organs-on-chips

2. Reconstituting Organ-Level Lung Functions on a Chip

3. Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow