The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells-Reference-Cited by-同舟云学术

The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells

Published:2017 Issue:39 Volume:53 Page:5441-5444
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sanllehí Pol¹²³⁴⁵,Casasampere Mireia¹²³⁴⁵,Abad José-Luis¹²³⁴⁵^ORCID,Fabriàs Gemma¹²³⁴⁵^ORCID,López Olga¹²⁶⁷⁵,Bujons Jordi¹²⁸⁹¹⁰,Casas Josefina¹²³⁴⁵^ORCID,Delgado Antonio¹²³⁴⁵^ORCID

Affiliation:

1. Spanish National Research Council (CSIC)

2. Institute of Advanced Chemistry of Catalonia (IQAC-CSIC)

3. Research Unit on Bioactive Molecules (RUBAM)

4. Department of Biomedicinal Chemistry

5. 08034 Barcelona

6. Group of Biophysics of Lipids and Interfaces (BLI)

7. Department of Chemical and Surfactants Technology

8. Department of Biological Chemistry and Molecular Modelling

9. 08034-Barcelona

10. Spain

Abstract

The first fluorogenic sensor for the quantification of S1PL activity in intact cells is reported.

Funder

Ministerio de Ciencia e Innovación

Fundació la Marató de TV3

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC01659J

Reference16 articles.

1. Sphingosine-1-phosphate lyase in immunity and cancer: silencing the siren

2. Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy

3. Inhibitors of sphingosine-1-phosphate metabolism (sphingosine kinases and sphingosine-1-phosphate lyase)

4. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency

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