Palladium-catalyzed directed synthesis of ortho-deuterated phenylacetic acid and analogues
Author:
Affiliation:
1. TCG Lifesciences Pvt. Ltd
2. Kolkata-700091
3. India
4. Department of Chemistry
5. University of Calcutta
6. Kolkata 700009
Abstract
An efficient method for directed ortho-selective H/D-exchange of 2-pyridone containing phenylacetic acid amides is presented which has been implemented to synthesize a medicinally important compound in gram scale with excellent deuterium enrichment.
Funder
Science and Engineering Research Board
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00663K
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