Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide
Author:
Affiliation:
1. Cixi Institute of Biomedical Engineering
2. Ningbo Institute of Materials Technology and Engineering
3. Chinese Academy of Sciences
4. Ningbo 315201
5. P. R. China
6. College of Science and Technology
7. Ningbo University
8. Ningbo 315212
Abstract
A facile peptide nucleic acid microarray-based fluorometric method was developed for sensitive and specific detection of EGFR mutation by using rolling circle amplification, graphene oxide, and a fluorescently-labeled detection probe.
Funder
Natural Science Foundation of Ningbo
China Postdoctoral Science Foundation
Chinese Academy of Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA06758B
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