Multiple 3D-QSAR modeling, e-pharmacophore, molecular docking, and in vitro study to explore novel AChE inhibitors-Reference-Cited by-同舟云学术

Multiple 3D-QSAR modeling, e-pharmacophore, molecular docking, and in vitro study to explore novel AChE inhibitors

Published:2018 Issue:69 Volume:8 Page:39477-39495
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jana Srabanti¹²³⁴⁵^ORCID,Ganeshpurkar Ankit¹²³⁴⁵^ORCID,Singh Sushil Kumar¹²³⁴⁵^ORCID

Affiliation:

1. Pharmaceutical Chemistry Research Laboratory

2. Department of Pharmaceutical Engineering & Technology

3. Indian Institute of Technology (Banaras Hindu University)

4. Varanasi-221005

5. India

Abstract

Ligand-based and energy-optimized structure-based approaches were helpful to obtain excellent candidates as non-toxic, PAS site selective, non-competitive AChE inhibitors.

Funder

Department of Biotechnology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA08198K

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