Engineering hyperthermostable rcSso7d as reporter molecule forin vitrodiagnostic tests-Reference-Cited by-同舟云学术

Engineering hyperthermostable rcSso7d as reporter molecule forin vitrodiagnostic tests

Published:2018 Issue:6 Volume:3 Page:877-882
ISSN:2058-9689
Container-title:Molecular Systems Design & Engineering
language:en
Short-container-title:Mol. Syst. Des. Eng.

Author:

Sung Ki-Joo¹²³⁴^ORCID,Miller Eric A.¹²³⁴,Sikes Hadley D.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemical Engineering

2. Massachusetts Institute of Technology

3. Cambridge

4. USA

5. Singapore-MIT Alliance for Research and Technology Centre (SMART)

Abstract

We investigated different constructs of the hyperthermostable binding protein, rcSso7d, to link a detectable signal to the presence of target biomarker.

Funder

National Research Foundation Singapore

National Science Foundation

Singapore-MIT Alliance for Research and Technology Centre

Deshpande Center for Technological Innovation, Massachusetts Institute of Technology

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Industrial and Manufacturing Engineering,Process Chemistry and Technology,Energy Engineering and Power Technology,Biomedical Engineering,Chemical Engineering (miscellaneous),Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2018/ME/C8ME00049B

Reference23 articles.

1. Engineering novel binding proteins from nonimmunoglobulin domains

2. Replacing Antibodies: Engineering New Binding Proteins

3. Challenges and opportunities for non-antibody scaffold drugs

4. Highly Stable Binding Proteins Derived from the Hyperthermophilic Sso7d Scaffold

5. In vitro-engineered non-antibody protein therapeutics

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