Asymmetric synthesis of chiral (thio)chromanes and exploration on their structure–activity relationship in macrophages-Reference-Cited by-同舟云学术

Asymmetric synthesis of chiral (thio)chromanes and exploration on their structure–activity relationship in macrophages

Published:2023 Issue:43 Volume:13 Page:30391-30400
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Xiao¹²,Zhou Qian³^ORCID,Zhou Yue³,Wang Zihao⁴⁵,Wang Jun²⁶^ORCID,Wang Mingfu¹³

Affiliation:

1. School of Biological Science, The University of Hong Kong, Hong Kong 999077, China

2. Department of Chemistry, Southern University of Science and Technology, Shenzhen 518055, China

3. Shenzhen Key Laboratory of Food Nutrition and Health, Institute for Advanced Study, Shenzhen University, Shenzhen 518060, China

4. School of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China

5. Centre for Chinese Herbal Medicine Drug Development, Hong Kong Baptist University, Hong Kong 999077, China

6. Department of Chemistry, Hong Kong Baptist University, Hong Kong 999077, China

Abstract

A CuCl/(R,R)-Ph-BPE-catalyzed enantioselective hydroallylation of 2H-(thio)chromenes is developed, which enables access to a series of 4-allyl (thio)chromanes in high yields (up to 91%) with excellent enantioselectivities (up to 99% ee).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA06428J

Reference49 articles.

1. Asymmetric synthesis of chiral chromans

2. L. J.Machlin , α-Tocopherol , Marcel Dekker , New York , 1980

3. Differential Effects of Green Tea–Derived Catechin on Developing Versus Established Atherosclerosis in Apolipoprotein E–Null Mice

4. Recent progress in the development of coumarin derivatives as potent anti-HIV agents