Efficient fabrication of thermo-stable dissolving microneedle arrays for intradermal delivery of influenza whole inactivated virus vaccine-Reference-Cited by-同舟云学术

Efficient fabrication of thermo-stable dissolving microneedle arrays for intradermal delivery of influenza whole inactivated virus vaccine

Published:2023 Issue:20 Volume:11 Page:6790-6800
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Lee Jihui¹,Beukema Martin²^ORCID,Zaplatynska Oliwia A.¹,O'Mahony Conor³,Hinrichs Wouter L. J.⁴,Huckriede Anke L. W.²,Bouwstra Joke A.¹,van der Maaden Koen¹⁵^ORCID

Affiliation:

1. Division of Biotherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands

2. Department of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, 9713AV Groningen, The Netherlands

3. Tyndall National Institute, Lee Maltings, Prospect Row, Cork, Ireland

4. Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, 9713AV Groningen, The Netherlands

5. Department of Immunology, Leiden University Medical Center, 2300RC Leiden, The Netherlands

Abstract

WIV incorporated dMNAs produced by the dispensing method reduced antigen waste by 95% compared to the centrifugation method. They also maintained the stability of WIV and elicited similar immune responses to intramuscularly (I.M.) delivered WIV.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00377A

Reference36 articles.

1. High-risk Groups for Influenza Complications

2. Influenza (Seasonal). [cited 2022 Sep 1]. Available from: https://www.who.int/en/news-room/fact-sheets/detail/influenza-(seasonal)

3. Influenza Vaccination and Mortality: Differentiating Vaccine Effects From Bias

4. Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Orally dissolving film as a potential vaccine delivery carrier to prevent influenza virus infection;Antiviral Research;2024-10

2. Recent progress of microneedles in transdermal immunotherapy: A review;International Journal of Pharmaceutics;2024-09

3. Effect of Triton X-100 surfactant and agitation on tetramethylammonium hydroxide wet etching for microneedle fabrication;Journal of Vacuum Science & Technology B;2024-09-01

4. Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices;Drug Delivery and Translational Research;2023-11-30