Anti selective glycolate aldol reactions of (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one: application towards the asymmetric synthesis of 8-4′-oxyneolignans-Reference-Cited by-同舟云学术

Anti selective glycolate aldol reactions of (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one: application towards the asymmetric synthesis of 8-4′-oxyneolignans

Published:2016 Issue:104 Volume:6 Page:102116-102126
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Gangar Mukesh¹²³⁴,Ittuveetil Avinash¹²³⁴,Goyal Sandeep¹²³⁴,Pal Anang¹²³⁴,Harikrishnan M. Harikrishnan M.¹²³⁴,Nair Vipin A.¹²³⁴

Affiliation:

1. Department of Medicinal Chemistry

2. National Institute of Pharmaceutical Education and Research

3. Mohali

4. India

Abstract

The anti selective glycolate aldol reactions of (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one auxiliary have been standardized with high yields and excellent diastereoselectivities on various substituted aryl, allyl and alkyl aldehydes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA22026F

Reference47 articles.

1. R. Mahrwald , in Modern Methods in Stereoselective Aldol Reactions, Wiley-VCH Verlag GmbH & Co. KGaA, 2013

2. Synthesis and stereoselective aldol reaction of dihydroxyacetone derivatives

3. Highly selective syn glycolate aldol reactions with boron enolates of Masamune norephedrine esters

4. Enantioselective Total Synthesis of (+)-Gigantecin: Exploiting the Asymmetric Glycolate Aldol Reaction

5. The total synthesis of the polyether antibiotic X-206

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