Discovery of a simple iron catalyst reveals the intimate steps of C–H amination to form C

Discovery of a simple iron catalyst reveals the intimate steps of C–H amination to form C–N bonds

Published:2023 Issue:11 Volume:14 Page:2849-2859
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Stroek Wowa¹^ORCID,Albrecht Martin¹^ORCID

Affiliation:

1. Department of Chemistry, Biochemistry, and Pharmaceutical Sciences, University of Bern, CH-3012 Bern, Switzerland

Abstract

Fe(HMDS)2 is an efficient catalyst for the intramolecular C–H amination using azides as nitrene precursors; its simplicity offers crucial insights into the mechanism of this reaction.

Funder

FP7 Ideas: European Research Council

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D2SC04170G

Reference72 articles.

1. Making carbon-nitrogen bonds in biological and chemical synthesis

2. Streamlining amine synthesis

3. A.Ricci , Amino Group Chemistry: From Synthesis to the Life Sciences , Wiley-VCH : Weinheim , 2008

4. C–N bond forming cross-coupling reactions: an overview

5. More Sustainable Approaches for the Synthesis of N-Based Heterocycles

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Heteroleptic Triazole–Bisoxazoline Iron Complexes Reveal Lability of the Iron–Carbene Bond Even Within a Chelating Scaffold;Inorganic Chemistry;2024-09-03

2. Iron Corrole‐Catalyzed Intramolecular Amination Reactions of Alkyl Azides. Spectroscopic Characterization and Reactivity of [Fe^V(Cor)(NAd)];Advanced Science;2024-08-20

3. Square-planar iron imido complexes containing strong-field pincer ligands as models for active species in catalytic nitrene transfer;Tetrahedron;2024-08

4. Iron-catalysed nitrene transfer reaction to form C N bonds;Tetrahedron Letters;2024-07

5. Homogeneous Iron Catalyzed C−H Amination;ChemCatChem;2024-06-12