Orthophosphate and alkaline phosphatase induced the formation of apatite with different multilayered structures and mineralization balance

Author:

Du Tianming1,Niu Yumiao1,Jia Zhenzhen2,Liu Youjun1,Qiao Aike1,Yang Haisheng1,Niu Xufeng2ORCID

Affiliation:

1. Beijing International Science and Technology Cooperation Base for Intelligent Physiological Measurement and Clinical Transformation, Department of Biomedical Engineering, Faculty of Environment and Life, Beijing University of Technology, Beijing 100124, China

2. Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China

Abstract

Apatite deposited on a collagen surface with different crystallinities and multilayered structures has been prepared. Orthophosphate and alkaline phosphatase are helpful for multilayered apatite formation and mineralization balance maintenance.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

China Postdoctoral Science Foundation

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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