Nucleophilic ring opening of aziridines with amines under catalyst- and solvent-free conditions-Reference-Cited by-同舟云学术

Nucleophilic ring opening of aziridines with amines under catalyst- and solvent-free conditions

Published:2017 Issue:4 Volume:19 Page:924-927
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Huang Yi-Yong¹²³⁴⁵^ORCID,Lv Zong-Chao¹²³⁴⁵,Yang Xing¹²³⁴⁵,Wang Zhao-Lei¹²³⁴⁵,Zou Xiao-Xue¹²³⁴⁵,Zhao Zhen-Ni¹²³⁴⁵,Chen Fei⁶⁷⁸⁹¹⁰

Affiliation:

1. Department of Chemistry

2. School of Chemistry

3. Chemical Engineering and Life Science

4. Wuhan University of Technology

5. Wuhan 430070

6. Beijing National Laboratory for Molecular Sciences (BNLMS)

7. Institute of Chemistry

8. Chinese Academy of Sciences

9. Beijing 100190

10. China

Abstract

Aza-addition of aziridines under catalyst- and solvent-free conditions was performed to provide access to a wide array of vicinal diamines in up to 95% yields, thus facilitating the scale-up synthesis of the 4-amino-1,2,3,4-tetrahydroisoquinoline derivative.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/GC/C6GC03144G

Reference70 articles.

1. Guanylated Diamines, Triamines, and Polyamines: Chemistry and Biological Properties

2. Vicinal Diamino Functionalities as Privileged Structural Elements in Biologically Active Compounds and Exploitation of their Synthetic Chemistry

3. Pushing the Limits of Aminocatalysis: Enantioselective Transformations of α-Branched β-Ketocarbonyls and Vinyl Ketones by Chiral Primary Amines