Opportunities and challenges in targeting orphan nuclear receptors-Reference-Cited by-同舟云学术

Opportunities and challenges in targeting orphan nuclear receptors

Published:2023 Issue:31 Volume:59 Page:4551-4561
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Isigkeit Laura¹^ORCID,Merk Daniel¹²^ORCID

Affiliation:

1. Goethe University Frankfurt, Institute of Pharmaceutical Chemistry, 60438 Frankfurt, Germany

2. Ludwig-Maximilians-Universität München, Department of Pharmacy, 81377 Munich, Germany

Abstract

Nuclear receptor modulation enables pharmacological control of gene expression and holds great therapeutic potential. Chemical tools are lacking for many nuclear receptors but needed to reveal new therapeutic opportunities.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC00954H

Reference131 articles.

1. Evolution of transcription factor binding in metazoans — mechanisms and functional implications

2. Transcription Factor Drug Targets

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4. Overview of Nomenclature of Nuclear Receptors

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