Cyclometalated iridium(iii) complexes induce mitochondria-derived paraptotic cell death and inhibit tumor growthin vivo-Reference-Cited by-同舟云学术

Cyclometalated iridium(iii) complexes induce mitochondria-derived paraptotic cell death and inhibit tumor growthin vivo

Published:2018 Issue:20 Volume:47 Page:6942-6953
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

He Liang¹²³⁴⁵,Wang Kang-Nan¹²³⁴⁵,Zheng Yue¹²³⁴⁵,Cao Jian-Jun¹²³⁴⁵,Zhang Ming-Fang¹²³⁴⁵,Tan Cai-Ping¹²³⁴⁵,Ji Liang-Nian¹²³⁴⁵,Mao Zong-Wan¹²³⁴⁵^ORCID

Affiliation:

1. MOE Key Laboratory of Bioinorganic and Synthetic Chemistry

2. School of Chemistry

3. Sun Yat-sen University

4. Guangzhou 510275

5. P. R. China

Abstract

A potent anticancer Ir(iii) complex induces paraptotic cell death by causing mitochondrial dysfunction rapidly and inhibits tumor growth significantlyin vivo.

Funder

National Natural Science Foundation of China

Ministry of Education of the People's Republic of China

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/DT/C8DT00783G

Reference82 articles.

1. Metal-based anticancer chemotherapeutic agents

2. The problem with platinum

3. Metal-based drugs that break the rules

4. Bioactive iridium and rhodium complexes as therapeutic agents

5. Organoiridium Complexes: Anticancer Agents and Catalysts

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