A microfluidic chip with double-sided herringbone microstructures for enhanced capture of rare tumor cells-Reference-Cited by-同舟云学术

A microfluidic chip with double-sided herringbone microstructures for enhanced capture of rare tumor cells

Published:2017 Issue:46 Volume:5 Page:9114-9120
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Wang Minjiao¹²³,Wang Zhihua⁴²³,Zhang Mingkan⁵⁶⁷,Guo Wei⁸⁹³,Li Ning⁸⁹³,Deng Yuliang¹²³,Shi Qihui¹²³¹⁰²^ORCID

Affiliation:

1. Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University

2. Shanghai

3. China

4. Laboratory of Gynaecologic Oncology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine

5. Department of Geology and Geophysics, University of Wyoming, Laramie

6. Wyoming

7. USA

8. Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

9. Beijing

10. Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Shanghai Jiao Tong University

Abstract

This paper reports an analytical model to geometrically optimize a herringbone chip by investigating the interactions between cells and antibody-immobilized device surfaces for enhancing CTC capture efficiency.

Funder

National Natural Science Foundation of China

Chinese Academy of Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB02318A

Reference17 articles.

1. Circulating tumor cells: approaches to isolation and characterization

2. Circulating tumor cells: the Grand Challenge

3. Isolation of rare circulating tumour cells in cancer patients by microchip technology

4. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

5. Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers

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