Ti3C2 MXene as a novel substrate provides rapid differentiation and quantitation of glycan isomers with LDI-MS

Author:

Jiang Yuming12345,Sun Jie12345,Cui Yi6789ORCID,Liu Huihui12345,Zhang Xiaoyong6789ORCID,Jiang Yurong1011129,Nie Zongxiu12345ORCID

Affiliation:

1. Beijing National Laboratory for Molecular Sciences

2. Key Laboratory for Analytical Chemistry for Living Biosystems

3. Institute of Chemistry

4. The Chinese Academy of Sciences

5. Beijing 100190

6. College of Chemistry

7. Nanchang University

8. Nanchang 330031

9. China

10. School of Optics and Photonics

11. Beijing Institute of Technology

12. Beijing 100081

Abstract

Here we report Ti3C2 MXene assisted LDI-LIFT-TOF/TOF for robust differentiation and relative quantitation of glycan isomers that differ in composition, connectivity and configuration.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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