Unified synthesis and cytotoxic activity of 8-O-methylfusarubin and its analogues

Author:

Vijitphan Pongsit12345,Rukachaisirikul Vatcharin12345,Muanprasat Chatchai62785,Iawsipo Panata9210115ORCID,Panprasert Jiraporn9210115,Tadpetch Kwanruthai12345ORCID

Affiliation:

1. Department of Chemistry and Center of Excellence for Innovation in Chemistry

2. Faculty of Science

3. Prince of Songkla University

4. Hat Yai

5. Thailand

6. Department of Physiology

7. Mahidol University

8. Bangkok 10400

9. Department of Biochemistry and Center of Excellence for Innovation in Chemistry

10. Burapha University

11. Chonburi 20131

Abstract

A unified total synthesis of 8-O-methylfusarubin, 8-O-methylanhydrofusarubin, fusarubin and anhydrofusarubin and their cytotoxic activities against six cancer cell lines are described.

Funder

Crown Property Bureau

National Science and Technology Development Agency

Prince of Songkla University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference45 articles.

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3. Pyranonaphthoquinone antibiotics—isolation, structure and biological activity

4. Antimicrobial activity of naphthoquinones from Fusaria

5. Pyranonaphthoquinones—isolation, biological activity and synthesis

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