An improved algorithm for resolving overlapping peaks in ion mobility spectrometry and its application to the separation of glycan isomers-Reference-Cited by-同舟云学术

An improved algorithm for resolving overlapping peaks in ion mobility spectrometry and its application to the separation of glycan isomers

Published:2023 Issue:21 Volume:148 Page:5514-5524
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Hu Xiangyang¹²,Zhou Junfei¹²,Li Junhui²³^ORCID,Gao Wenqing²³^ORCID,Zhou Jun⁴,Yu Jiancheng¹²³,Tang Keqi²³^ORCID

Affiliation:

1. Faculty of Electrical Engineering and Computer Science, Ningbo University, Ningbo, P. R. China

2. Zhejiang Engineering Research Center of Advanced Mass Spectrometry and Clinical Application, Institute of Mass Spectrometry, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, P. R. China

3. Ningbo Zhenhai Institute of Mass Spectrometry, Ningbo, P.R. China

4. Zhejiang Ningbo Ecological and Environmental Monitoring Center, Ningbo, P.R. China

Abstract

An improved algorithm for resolving overlapping peaks in ion mobility spectrometry was proposed and successfully applied to the separation of glycan isomers from both standard glycan overlapping peaks and real samples.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

K. C. Wong Magna Fund in Ningbo University

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AN/D3AN01042B

Reference31 articles.

1. Identification and Quantification of Any Isoforms of Carbohydrates by 2D UV-MS Fingerprinting of Cold Ions

2. Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis

3. Glycan Analysis by Ion Mobility-Mass Spectrometry

4. Dissecting Total Plasma and Protein-Specific Glycosylation Profiles in Congenital Disorders of Glycosylation

5. Mass Spectrometry Approach for Differentiation of Positional Isomers of Saccharides: Toward Direct Analysis of Rare Sugars

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