Synthesis of alcohols: streamlined C1 to Cn hydroxyalkylation through photoredox catalysis

Author:

Pasca Francesco1,Gelato Yuri1,Andresini Michael1ORCID,Romanazzi Giuseppe2ORCID,Degennaro Leonardo1ORCID,Colella Marco1ORCID,Luisi Renzo1ORCID

Affiliation:

1. Department of Pharmacy-Drug Sciences, Flow Chemistry and Microreactor Technology FLAME-Lab University of Bari “A. Moro”, Via E. Orabona 4, 70125 Bari, Italy

2. DICATECh Politecnico di Bari, Via E. Orabona 4, Bari 70125, Italy

Abstract

Naturally occurring and readily available α-hydroxy carboxylic acids (AHAs) are utilized as platforms for visible light-mediated oxidative CO2-extrusion furnishing α-hydroxy radicals proved to be versatile C1 to Cn hydroxyalkylating agents.

Funder

European Health and Digital Executive Agency

Ministero dell'Istruzione e del Merito

Publisher

Royal Society of Chemistry (RSC)

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