Liquid–liquid phase separation rescues the conformational stability of a DNA hairpin from pressure

Liquid–liquid phase separation rescues the conformational stability of a DNA hairpin from pressure–stress

Published:2019 Issue:72 Volume:55 Page:10673-10676
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Arns Loana¹²³⁴⁵^ORCID,Winter Roland¹²³⁴⁵^ORCID

Affiliation:

1. Physical Chemistry I – Biophysical Chemistry

2. Faculty of Chemistry and Chemical Biology

3. TU Dortmund University

4. D-44227 Dortmund

5. Germany

Abstract

Aqueous two-phase systems are able to rescue the conformational stability of DNA hairpins under harsh environmental conditions.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC04967C

Reference33 articles.

1. Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

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3. Physical principles of intracellular organization via active and passive phase transitions

4. Aqueous Phase Separation as a Possible Route to Compartmentalization of Biological Molecules

5. RNA catalysis through compartmentalization

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