The alleviating effect of ellagic acid on DSS-induced colitis via regulating gut microbiomes and gene expression of colonic epithelial cells

Author:

Li Xiaoqing12ORCID,Xu Lu1,Peng Xinan1,Zhang Huiting1,Kang Meng1,Jiang Yiqi1,Shi Haibo2,Chen Haiyan3,Zhao Chao4ORCID,Yu Yigang2,Ma Ruiting5,Li Xueli5,Cao Yong1

Affiliation:

1. Guangdong Provincial Key Laboratory of Nutraceuticals and Functional Foods, College of Food Science, South China Agricultural University, 483 Wushan Road, Tianhe District, Guangzhou City, Guangdong Province, 510642, China

2. College of Food Science and Engineering, South China University of Technology, Guangzhou 510006, China

3. Guangdong Testing Institute of Product Quality Supervision (GQI), Foshan, 528300, China

4. College of Marine Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China

5. Eastroc Beverage Group Co., Ltd, Shenzhen, 518057, China

Abstract

The anti-inflammatory effect of ellagic acid (EA) and its possible underlying mechanism in dextran sulfate sodium (DSS)-induced mouse chronic colonic inflammation were studied.

Funder

Guangdong Innovative and Entrepreneurial Research Team Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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