Rational design of oxygen deficient TiO2−x nanoparticles conjugated with chlorin e6 (Ce6) for photoacoustic imaging-guided photothermal/photodynamic dual therapy of cancer

Author:

Jiao Xiaodan12345,Zhang Wei678910,Zhang Lei1141213,Cao Yang678910,Xu Zhigang12345ORCID,Kang Yuejun12345ORCID,Xue Peng12345ORCID

Affiliation:

1. Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University)

2. Ministry of Education

3. School of Materials and Energy

4. Southwest University

5. Chongqing 400715

6. Chongqing Key Laboratory of Ultrasound Molecular Imaging

7. Institute of Ultrasound Imaging

8. Second Affiliated Hospital

9. Chongqing Medical University

10. Chongqing

11. Institute of Sericulture and System Biology

12. Chongqing 400716

13. China

Abstract

Surface activation of TiO2−x NPs by APTES and subsequent Ce6 conjugation enabled highly efficient PA imaging-guided PTT/PDT.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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