A microfluidic model to study the effects of arrhythmic flows on endothelial cells-Reference-Cited by-同舟云学术

A microfluidic model to study the effects of arrhythmic flows on endothelial cells

Published:2024 Issue:8 Volume:24 Page:2347-2357
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Lai Austin¹²,Hawke Adam³^ORCID,Mohammed Mokhaled³^ORCID,Thurgood Peter²³^ORCID,Concilia Gianmarco³^ORCID,Peter Karlheinz²⁴,Khoshmanesh Khashayar²³^ORCID,Baratchi Sara¹²⁴^ORCID

Affiliation:

1. School of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria, Australia

2. Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia

3. School of Engineering, RMIT University, Melbourne, Victoria, Australia

4. Baker Department of Cardiometabolic Health, University of Melbourne, Melbourne, Victoria, Australia

Abstract

We created a versatile microfluidic system for studying the effect of arrhythmic flow patterns on endothelial cells in vitro. This system provides unique opportunities to identify the molecular machineries that control endothelial biology in response to arrhythmia.

Funder

Australian Government

Australian Research Council

National Health and Medical Research Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/LC/D3LC00834G

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