Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform-Reference-Cited by-同舟云学术

Droplet-assisted electrospray phase separation using an integrated silicon microfluidic platform

Published:2022 Issue:1 Volume:22 Page:40-46
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Zhang Yan¹,Kim Sungho¹^ORCID,Shi Weihua¹,Zhao Yaoyao²,Park Insu³,Brenden Christopher³^ORCID,Iyer Hrishikesh¹,Jha Prasoon¹,Bashir Rashid³^ORCID,Sweedler Jonathan V.²^ORCID,Vlasov Yurii¹³^ORCID

Affiliation:

1. Department of Electrical and Computer Engineering, University of Illinois Urbana Champaign, IL 61801, USA

2. Department of Chemistry and the Beckman Institute, University of Illinois Urbana Champaign, IL 61801, USA

3. Department of Bioengineering, University of Illinois Urbana Champaign, IL 61801, USA

Abstract

We report on a silicon microfluidic platform that enables integration of transparent μm-scale microfluidic channels, an on-chip pL-volume droplet generator, and a nano-electrospray ionization emitter that enables spatial and temporal phase separation for mass spectrometry analysis.

Funder

National Institute of Neurological Disorders and Stroke

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC00758K

Reference38 articles.

1. High-throughput screening by droplet microfluidics: perspective into key challenges and future prospects

2. A droplet-chip/mass spectrometry approach to study organic synthesis at nanoliter scale

3. Conversion Efficiencies of a Few Living Microbial Cells Detected at a High Throughput by Droplet-Based ESI-MS