Fine-tuning of the hydrophobicity of caffeic acid: studies on the antimicrobial activity against Staphylococcus aureus and Escherichia coli
Author:
Affiliation:
1. LEPABE
2. Department of Chemical Engineering
3. Faculty of Engineering
4. University of Porto
5. Portugal
6. CIQUP
7. Department of Chemistry and Biochemistry
8. Faculty of Sciences
9. Porto
Abstract
Caffeic acid derivatives are proposed to act as cell permeabilizers, inducing membrane alterations, causing rupture with potassium leakage, particularly on the Gram positive bacterium, and consequent cell death.
Funder
Fundação para a Ciência e a Tecnologia
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA05840F
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