PRESCIENT: platform for the rapid evaluation of antibody success using integrated microfluidics enabled technology

Author:

Wippold Jose A.123ORCID,Wang Han14567,Tingling Joseph89103,Leibowitz Julian L.89103,de Figueiredo Paul8910311,Han Arum123122ORCID

Affiliation:

1. Department of Biomedical Engineering

2. Texas A&M University

3. USA

4. School of Medicine

5. Tsinghua University

6. Beijing

7. China

8. Department of Microbial Pathogenesis and Immunology

9. Texas A&M Health Science Center

10. Bryan

11. Norman Borlaug Center

12. Department of Electrical and Computer Engineering

Abstract

Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents.

Funder

Texas A and M University

U.S. Department of Defense

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Reference45 articles.

1. History and Practice: Antibodies in Infectious Diseases

2. Therapeutic antibodies: successes, limitations and hopes for the future

3. Antibody Discovery: Sourcing of Monoclonal Antibody Variable Domains

4. The role of phage display in therapeutic antibody discovery

5. C. R. Geyer , J.McCafferty , S.Dübel , A. R. M.Bradbury and S. S.Sidhu , Recombinant Antibodies and In Vitro Selection Technologies, Antibody Methods and Protocols , ed. G. Proetzel and H. Ebersbach , Humana Press , Totowa, NJ , 2012 , pp. 11–32

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