TfOH mediated intermolecular electrocyclization for the synthesis of pyrazolines and its application in alkaloid synthesis-Reference-Cited by-同舟云学术

TfOH mediated intermolecular electrocyclization for the synthesis of pyrazolines and its application in alkaloid synthesis

Published:2018 Issue:53 Volume:8 Page:30071-30075
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Annes Sesuraj Babiola¹²³⁴⁵,Vairaprakash Pothiappan¹²³⁴⁵^ORCID,Ramesh Subburethinam¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. School of Chemical and Biotechnology

3. SASTRA Deemed University

4. Thanjavur

5. India

Abstract

A metal free and green synthetic methodology employing aldehydes, phenylhydrazine and styrene mediated by TfOH has been developed to access 1,3,5-trisubstituted pyrazolines. The synthetic application of the methodology is demonstrated in the synthesis of a pyrazoline alkaloid.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA05702H

Reference45 articles.

1. A Comprehensive Review on Recent Developments in the Field of Biological Applications of Potent Pyrazolines Derived from Chalcone Precursors

2. Pyrazolines: A Biological Review

3. From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles