Catalyst- and solvent-free Csp2–H functionalization of 4-hydroxycoumarins via C-3 dehydrogenative aza-coupling under ball-milling-Reference-Cited by-同舟云学术

Catalyst- and solvent-free Csp2–H functionalization of 4-hydroxycoumarins via C-3 dehydrogenative aza-coupling under ball-milling

Published:2021 Issue:13 Volume:23 Page:4762-4770
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Brahmachari Goutam¹²³⁴^ORCID,Karmakar Indrajit¹²³⁴,Karmakar Pintu¹²³⁴

Affiliation:

1. Laboratory of Natural Products & Organic Synthesis

2. Department of Chemistry

3. Visva-Bharati (a Central University)

4. India

Abstract

A mechanochemistry-driven green and efficient synthetic protocol for bio-relevant coumarin-hydrazones from a one-pot three-component reaction between 4-hydrocoumarins, primary aromatic amines and tert-butyl nitrite under ball-milling has been developed.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/GC/D1GC01341F

Reference115 articles.

1. Carbon–heteroatom bond formation catalysed by organometallic complexes

2. Nitrosonium ion catalysis: aerobic, metal-free cross-dehydrogenative carbon–heteroatom bond formation

3. A. K. Yudin and J. F.Hartwig , Catalyzed Carbon-Heteroatom Bond Formation , Wiley-VCH , Weinheim , 2010