Genetically encodable biosensors for Ras activity

Author:

Weeks Ryan12ORCID,Mehta Sohum2ORCID,Zhang Jin123ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA

2. Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA

3. Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA

Abstract

Genetically encoded Ras biosensors have illuminated the spatiotemporal dynamics of Ras activity since the start of the imaging revolution of the early 21st century, helping elucidate Ras signalling at various subcellular compartments.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

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