Structure–antitumor activity relationships of tripodal imidazolium-amino acid based salts. Effect of the nature of the amino acid, amide substitution and anion-Reference-Cited by-同舟云学术

Structure–antitumor activity relationships of tripodal imidazolium-amino acid based salts. Effect of the nature of the amino acid, amide substitution and anion

Published:2021 Issue:48 Volume:19 Page:10575-10586
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Valls Adriana¹^ORCID,Altava Belén¹^ORCID,Aseyev Vladimir²,Carreira-Barral Israel³^ORCID,Conesa Laura¹,Falomir Eva¹,García-Verdugo Eduardo¹^ORCID,Luis Santiago Vicente¹^ORCID,Quesada Roberto³^ORCID

Affiliation:

1. Department of Inorganic and Organic Chemistry, ESTCE, University Jaume I, Av. Sos Baynat, s/n, 12004, Castellón, Spain

2. Department of Chemistry, University of Helsinki, P.O. Box 55 (A413, A. I. Virtasen aukio 1), FIN-00014 HY Helsinki, Finland

3. Department of Chemistry, Faculty of Science, Universidad de Burgos, 09001 Burgos, Spain

Abstract

Imidazolium tripodal compounds derived from amino acids presented good cancer cell growth inhibition against different cancer cell lines, increasing the inhibition when in vitro experiments were carried out at acidic pHe.

Funder

Ministerio de Ciencia, Innovación y Universidades

Consejería de Educación, Junta de Castilla y León

Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital, Generalitat Valenciana

Universitat Jaume I

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01825F

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