Ciprofloxacin salts of benzene mono/di-carboxylate: crystal structures and the improvement of solubility-Reference-Cited by-同舟云学术

Ciprofloxacin salts of benzene mono/di-carboxylate: crystal structures and the improvement of solubility

Published:2024 Issue:20 Volume:26 Page:2662-2672
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Zhu Yujun¹,Liu Ruoxi²^ORCID,Wang Leyao²^ORCID,Chen Chen²,Zhao Yupei²^ORCID,Guo Wei³,Zhang Zhihui²^ORCID

Affiliation:

1. Department of Pharmacy and Biomedical Engineering, Clinical College of Anhui Medical University, Hefei 230031, P.R. China

2. Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Changzhou University, Changzhou 213164, P.R. China

3. School of Pharmaceutical Science, Hebei Medical University, Shijiazhuang 050017, P.R. China

Abstract

Ciprofloxacin salts were constructed and structurally characterized through single-crystal X-ray diffractions. The cocrystallization of benzene carboxylates, including salicylate coformers, may significantly improve the solubility of ciprofloxacin.

Funder

Anhui Provincial Department of Education

Natural Science Foundation of Hebei Province

Qinglan Project of Jiangsu Province of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CE/D4CE00213J

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