Dithioallyl cation (3 + 2) cycloadditions under aprotic reaction conditions: rapid access to spiro-fused cyclopentane scaffolds-Reference-Cited by-同舟云学术

Dithioallyl cation (3 + 2) cycloadditions under aprotic reaction conditions: rapid access to spiro-fused cyclopentane scaffolds

Published:2023 Issue:40 Volume:21 Page:8117-8124
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Degroote Frederick¹^ORCID,Denoo Bram¹,Ryckaert Bram¹,Callebaut Brenda¹,Van Hecke Kristof²^ORCID,Hullaert Jan¹,Winne Johan M.¹^ORCID

Affiliation:

1. OSgroup, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281-S4, 9000 Ghent, Belgium

2. XStruct, Department of Chemistry, Ghent University, Krijgslaan 281-S3, 9000 Ghent, Belgium

Abstract

Acid-sensitive conjugated alkenes can be transformed into attractive spirocarbocycles, using a newly developed mild generation mode of (thio)allyl cations giving a regio- and stereoselective carbocationic cascade reaction.

Funder

Fonds Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01273E

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