Construction of fluorescence logic gates responding to telomerase and miRNA based on DNA-templated silver nanoclusters and the hybridization chain reaction

Author:

Jiang Yiting12,Guo Zhenzhen23,Wang Mingyuan4,Cui Jinjiang23,Miao Peng12ORCID

Affiliation:

1. University of Science and Technology of China, Hefei 230026, China

2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China

3. Ji Hua Laboratory, Foshan 528200, China

4. Suzhou Blood Center, Suzhou 215006, China

Abstract

Logic gated operations are designed to respond to telomerase and miRNA, which are based on strand displacement reactions and the hybridization chain reaction with DNA-templated silver nanoclusters generating fluorescence as the output.

Funder

Chinese Academy of Sciences

Science and Technology Program of Suzhou

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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