Blocking tau transmission by biomimetic graphene nanoparticles-Reference-Cited by-同舟云学术

Blocking tau transmission by biomimetic graphene nanoparticles

Published:2023 Issue:31 Volume:11 Page:7378-7388
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhu Runyao¹^ORCID,Makwana Kamlesh M.²^ORCID,Zhang Youwen¹,Rajewski Benjamin H.²^ORCID,Del Valle Juan R.²^ORCID,Wang Yichun¹^ORCID

Affiliation:

1. Department of Chemical & Biomolecular Engineering, University of Notre Dame, Indiana 46556, USA

2. Department of Chemistry & Biochemistry, University of Notre Dame, Indiana 46556, USA

Abstract

Graphene quantum dots with engineered properties are able to block the seeding activity of tau fibrils by inhibiting the fibrillization of monomeric tau and triggering the disaggregation of tau filaments.

Funder

American Cancer Society

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB00850A

Reference56 articles.

1. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

2. The role of tau (MAPT) in frontotemporal dementia and related tauopathies

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5. Stability properties of neuronal microtubules

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