Fragment-based approach to study fungicide-biomimetic membrane interactions

Author:

Jaikishan Shishir1,Lavainne Marine1ORCID,Ravald Henri K.1,Scobbie Kieran1,Dusa Filip2,Maheswari Rekha1,Turpeinen Jenni1,Eikemans Ian1,Chen Rui1,Rantala Julia1,Aseyev Vladimir1,Maier Norbert N.1,Wiedmer Susanne K.1ORCID

Affiliation:

1. Department of Chemistry, A.I. Virtasen aukio 1, POB 55, 00014 University of Helsinki, Finland

2. Institute of Analytical Chemistry, Czech Academy of Sciences, Veveří 97, Brno 60200, Czech Republic

Abstract

Molecular interactions of the allylamine-type fungicide butenafine and a set of substructures with biomimetic liposomes were studied to gain a better understanding of the structural factors governing membrane affinity and perturbation.

Funder

Suomen Tiedeseura

Waldemar von Frenckells Stiftelse

Publisher

Royal Society of Chemistry (RSC)

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