Mitochondrion-targeted platinum complexes suppressing lung cancer through multiple pathways involving energy metabolism-Reference-Cited by-同舟云学术

Mitochondrion-targeted platinum complexes suppressing lung cancer through multiple pathways involving energy metabolism

Published:2019 Issue:10 Volume:10 Page:3089-3095
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhu Zhenzhu¹²³⁴⁵^ORCID,Wang Zenghui⁶⁷³⁴⁵,Zhang Changli⁸⁹⁴⁵,Wang Yanjun¹²³⁴⁵,Zhang Hongmei¹²³⁴⁵,Gan Zhenji¹¹⁰⁴⁵^ORCID,Guo Zijian⁶⁷³⁴⁵^ORCID,Wang Xiaoyong¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Pharmaceutical Biotechnology

2. School of Life Sciences

3. Nanjing University

4. Nanjing

5. P. R. China

6. State Key Laboratory of Coordination Chemistry

7. School of Chemistry and Chemical Engineering

8. School of Biochemical and Environmental Engineering

9. Nanjing Xiaozhuang University

10. Model Animal Research Center of Nanjing University

Abstract

Monofunctional platinum complexes restrain lung cancer through disrupting mitochondrial oxidative phosphorylation and glycolysis in addition to damaging nuclear and mitochondrial DNA.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC04871A

Reference50 articles.

1. Bevacizumab in combination with anticancer drugs for previously treated advanced non-small cell lung cancer