Single dose combination nanovaccine provides protection against influenza A virus in young and aged mice

Author:

Ross Kathleen12345,Senapati Sujata1234ORCID,Alley Jessica6234,Darling Ross7234,Goodman Jonathan1234,Jefferson Matthew8234,Uz Metin1234,Guo Baoqing9234,Yoon Kyoung-Jin9234,Verhoeven David72345,Kohut Marian62345,Mallapragada Surya12345,Wannemuehler Michael72345,Narasimhan Balaji12345ORCID

Affiliation:

1. Chemical & Biological Engineering

2. Iowa State University

3. Ames

4. USA

5. Nanovaccine Institute

6. Kinesiology

7. Veterinary Microbiology & Preventive Medicine

8. Neuroscience

9. Veterinary Diagnostic and Production Animal Medicine

Abstract

Combined polyanhydride nanoparticles and pentablock copolymer micelles provide protection against homologous challenge in aged mice.

Funder

Iowa State University

Medical Research and Materiel Command

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Reference56 articles.

1. Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States

2. Influenza-Associated Hospitalizations in the United States

3. The annual impact of seasonal influenza in the US: Measuring disease burden and costs

4. Centers for Disease Control (CDC), Estimated influenza illnesses, medical visits, hospitalizations, and deaths in the United States- 2017–2018 influenza season, http://www.cdc.gov

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