Towards 213Bi alpha-therapeutics and beyond: unravelling the foundations of efficient BiIII complexation by DOTP-Reference-Cited by-同舟云学术

Towards 213Bi alpha-therapeutics and beyond: unravelling the foundations of efficient BiIII complexation by DOTP

Published:2021 Issue:16 Volume:8 Page:3893-3904
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Horváth Dávid¹²³⁴^ORCID,Travagin Fabio⁵⁶⁷⁸^ORCID,Guidolin Nicol⁹¹⁰¹¹⁸^ORCID,Buonsanti Federica⁹¹⁰¹¹⁸,Tircsó Gyula¹²³⁴^ORCID,Tóth Imre¹²³⁴¹²^ORCID,Bruchertseifer Frank¹³¹⁴¹⁵¹⁶,Morgenstern Alfred¹³¹⁴¹⁵¹⁶,Notni Johannes¹⁷¹⁸¹⁹²⁰¹⁶^ORCID,Giovenzana Giovanni B.⁵⁶⁷⁸²¹^ORCID,Baranyai Zsolt⁹¹⁰¹¹⁸^ORCID

Affiliation:

1. Department of Physical Chemistry

2. University of Debrecen

3. Debrecen

4. Hungary

5. Dipartimento di Scienze del Farmaco

6. Università del Piemonte Orientale “A. Avogadro” Largo Donegani 2/3

7. Novara

8. Italy

9. Bracco Research Center

10. Bracco Imaging SpA

11. 10010 Colleretto Giacosa (TO)

12. Department of Inorganic and Analytical Chemistry

13. European Commission

14. Joint Research Centre (JRC)

15. Karlsruhe

16. Germany

17. Institute of Pathology

18. Klinikum rechts der Isar

19. Technische Universität München

20. 81675 München

21. CAGE Chemicals

Abstract

Bi^III-DOTP complex is characterised by a fast formation kinetics, an outstanding thermodynamic stability and an impressive kinetic interness, making Bi^III-DOTP an optimal model for the development of targeted α-therapy (TAT) radiopharmaceuticals.

Funder

National Research, Development and Innovation Office

Università degli Studi del Piemonte Orientale

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QI/D1QI00559F

Reference68 articles.

1. Utilizing High-Energy γ-Photons for High-Resolution 213Bi SPECT in Mice