Origins of high catalyst loading in copper(i)-catalysed Ullmann–Goldberg C–N coupling reactions-Reference-Cited by-同舟云学术

Origins of high catalyst loading in copper(i)-catalysed Ullmann–Goldberg C–N coupling reactions

Published:2017 Issue:10 Volume:8 Page:7203-7210
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Sherborne Grant J.¹²³⁴⁵,Adomeit Sven⁶⁷⁸,Menzel Robert¹²³⁴⁵,Rabeah Jabor⁶⁷⁸,Brückner Angelika⁶⁷⁸,Fielding Mark R.⁹¹⁰¹¹⁵,Willans Charlotte E.¹²³⁴⁵,Nguyen Bao N.¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Process Research & Development

2. School of Chemistry

3. University of Leeds

4. Leeds

5. UK

6. Leibniz Institut für Katalyse e.V

7. Rostock

8. Germany

9. AstraZeneca

10. Pharmaceutical Technology and Development

11. Macclesfield

Abstract

A mechanistic investigation of Ullmann–Goldberg reactions using common bases led to the identification of pathways for catalyst deactivation. The solid form of the inorganic phase was found to have critical influence on the mechanism of the reaction.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC02859H

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