Hmboff/on as a switchable thiol protecting group for native chemical ligation-Reference-Cited by-同舟云学术

Hmboff/on as a switchable thiol protecting group for native chemical ligation

Published:2016 Issue:18 Volume:14 Page:4194-4198
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Qi Yun-Kun¹²³⁴⁵,Tang Shan¹²³⁴⁵,Huang Yi-Chao¹²³⁴⁵,Pan Man¹²³⁴⁵,Zheng Ji-Shen⁶⁷⁸⁹,Liu Lei¹²³⁴⁵

Affiliation:

1. Tsinghua-Peking Center for Life Sciences

2. Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education)

3. Department of Chemistry

4. Tsinghua University

5. Beijing 100084

6. High Magnetic Field Laboratory

7. Chinese Academy of Sciences

8. Hefei 230031

9. China

Abstract

A new thiol protecting group Hmb^off/on is described, which has a switchable activity that may be useful in the chemical synthesis of complex proteins or peptides.

Funder

Natural Science Foundation of Anhui Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00450D

Reference53 articles.

1. Synthesis of Proteins by Native Chemical Ligation

2. Total chemical synthesis of proteins

3. The critical role of peptide chemistry in the life sciences

4. Chemical Synthesis and Biological Function of Lipidated Proteins

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent advances in chemical protein synthesis: method developments and biological applications;Science China Chemistry;2024-03-12

2. Design, synthesis and anticancer evaluation of novel oncolytic peptide-chlorambucil conjugates;Bioorganic Chemistry;2023-09

3. Discovery, synthesis, and optimization of teixobactin, a novel antibiotic without detectable bacterial resistance;Journal of Peptide Science;2022-06-13

4. 2-Hydroxy-4-methoxybenzyl as a Thiol-Protecting Group for Directed-Disulfide Bond Formation;Organic Letters;2022-05-02

5. DIC/Oxyma‐based accelerated synthesis and oxidative folding studies of centipede toxin RhTx;Journal of Peptide Science;2021-09-12